EISSN: 2980-0749
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2004, Volume 2, Number 3, Page(s) 127-136
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Experimental Models of Diabetes Mellitus
Seda V. İrer, Gülinnaz Alper
Ege Üniversitesi Tıp Fakültesi, Biyokimya Anabilim Dalı, İzmir
Keywords: Experimental diabetes, Diabetes Mellitus, animal, rat

In research studies performed to enlighten the diagnosis and pathogenesis of various diseases and to investigate possible treatment strategies, experimental animal models provide many advantages to the investigators. Diabetes Mellitus is a chronic metabolic disease which lasts for whole life, requiring continuous follow-up and therapy. With its acute and chronic complications, it decreases patient's lifespan and quality, causes a high morbidity and mortality rate and is a huge economic burden. Therefore clarifying its pathogenesis has a great value. In this review, experimental models and their application procedures used in research studies examining pathogenesis of diabetes and its therapoetic approaches are discussed.

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